Ancient viral DNA may spark human life's first moments

Ancient viral DNA may spark human life's first moments, study suggests.

Why it matters

  • Ancient viral DNA remnants play a crucial role in early human development.
  • Shows how evolution repurposes old genetic material.

By the numbers

  • Up to 9% of our DNA is from ancient viruses.
  • LTR5Hs appeared around 5 million years ago.
  • Disabling LTR5Hs caused developmental failure in a 3D model of a blastocyst.

The big picture

  • Viral remnants integrated into our genome are essential for early development.
  • Evolution repurposes old genetic material for new functions.

What they're saying

  • One comment suggests support for the idea that viruses aren't alive but arise from internal RNA mechanisms.

Caveats

  • Study used a model (blastoid) rather than actual human embryos.
  • More research needed to confirm findings.

What’s next

  • Further research to understand mechanisms and implications.