Artificial sweeteners linked to cognitive decline in large study

Higher intake of artificial sweeteners linked to faster cognitive decline over 8 years, especially in diabetics.

Why it matters

  • Artificial sweeteners are widely used as sugar substitutes.
  • Cognitive decline is a major public health concern.
  • Findings could impact dietary recommendations.

By the numbers

  • 12,000+ participants followed for 8 years.
  • 62% faster cognitive decline in high consumers.
  • Highest intake group averaged 191 mg/day, equivalent to one can of diet soda.

The big picture

  • Artificial sweeteners may not be as safe as previously thought.
  • Stronger effects seen in diabetics suggest a potential vulnerability.
  • Study highlights the need for more research on long-term effects of sweeteners.

What they're saying

  • Skepticism about causation due to observational nature of the study.
  • Questions about linking chemically different substances to the same outcome.
  • Concerns about self-reported dietary data and potential confounding factors.

Caveats

  • Observational study cannot prove causation.
  • Self-reported dietary data may not reflect long-term habits.
  • Underlying health conditions could contribute to cognitive decline.

What’s next

  • More research with repeated dietary assessments and biomarkers.
  • Studies on different types of sweeteners and specific populations.
  • Potential changes in dietary guidelines based on further findings.