Brain protein may reverse age-related memory loss
Reducing FTL1 protein reversed memory loss in older mice, study finds.
Why it matters
- FTL1 protein linked to memory loss.
- Reversing FTL1 restored memory in mice.
- New target for cognitive decline treatments.
By the numbers
- High FTL1 in older mice' hippocampus.
- Reduced FTL1 improved memory and synapses.
- FTL1 also slowed metabolism in hippocampal cells.
The big picture
- FTL1 could reverse cognitive decline.
- Brain aging may be more reversible than thought.
- Potential for Alzheimer's treatments.
What they're saying
- Villeda: "True reversal of impairments."
Caveats
- Mouse study; human effects unknown.
- More research needed.
What’s next
- Develop FTL1-targeted therapies.
- Future human trials possible.