Brain shape changes linked to cognitive decline

New research links changes in brain shape to cognitive decline, offering insights into early dementia detection.

Why it matters

  • Understanding dementia risk can improve care and treatments.
  • Early detection is crucial for managing neurodegenerative diseases.

By the numbers

  • Study analyzed 2,603 MRI brain scans.
  • Participants aged 30 to 97.

The big picture

  • Brain shape changes unevenly with age, linked to cognitive decline.
  • Pressure on the entorhinal cortex may explain Alzheimer's pathology.

What they're saying

  • Researchers suggest this could be a new way to think about Alzheimer's mechanisms and early detection.

Caveats

  • More data needed to establish precise relationships.

What’s next

  • Team plans to explore why some brain areas expand with age and its relation to cognition.