CBD worsens cannabis effects in schizophrenia patients
A study found that CBD worsened memory and psychotic symptoms in schizophrenia patients using cannabis.
Why it matters
- CBD, often thought to protect against THC's adverse effects, may not help schizophrenia patients.
- This challenges previous beliefs about CBD's protective role.
By the numbers
- Study involved a double-blind, randomized, placebo-controlled, crossover trial.
- THC doses: 20 mg, 40 mg, 60 mg.
- CBD dose: 1000 mg oral.
The big picture
- Schizophrenia patients may face increased risks when using cannabis, especially with CBD.
- Findings suggest CBD may not be universally protective against cannabis-induced symptoms.
What they're saying
- Some commenters note that the study's scope is limited to schizophrenia patients and may not apply to others.
- One commenter questioned the use of oral CBD instead of inhaled.
Caveats
- The study was conducted in patients with comorbid CUD, so results may not apply to those without schizophrenia.
- Findings may not generalize to non-schizophrenia populations.
What’s next
- Further research is needed to understand CBD's effects in different populations and administration methods.