Daily vitamin B3 dose cuts skin cancer risk by up to 54%

A common vitamin B3 supplement may reduce skin cancer risk by up to 54%, especially for those with previous diagnoses.

Why it matters

  • Vitamin B3 (niacinamide) is a cheap, over-the-counter supplement that could significantly lower skin cancer risk.
  • Skin cancer is a major health issue, with billions spent annually on treatment in the US alone.

By the numbers

  • Study size: 33,822 individuals
  • Average risk reduction: 14%
  • Risk reduction for those with previous diagnosis: 54%
  • Largest effect seen in squamous cell carcinoma

The big picture

  • This study supports earlier findings from a 2015 Australian trial.
  • Niacinamide is thought to help skin cells repair UV-induced DNA damage.
  • More diverse studies are needed to confirm these findings in broader populations.

What they're saying

  • Users shared personal stories of B3's effectiveness.
  • One user warned about potential overdosing but noted it's less risky than some other vitamins.
  • Another user pointed out that B3 is already added to all bread products in the US.

Caveats

  • The study was observational, so causation can't be proven.
  • The cohort was mostly older, white men, so more diverse studies are needed.

What’s next

  • Further studies on diverse populations to confirm and expand these findings.
  • More research on the optimal timing and dosage for B3 supplementation.