Deep brain stimulation shows promise for treatment-resistant depression

Deep brain stimulation improved symptoms in half of patients with treatment-resistant depression in a new study.

Why it matters

  • Treatment-resistant depression affects many.
  • Current treatments fail for 30-50% of patients.
  • DBS could be a promising alternative.

By the numbers

  • 26 participants.
  • 50% saw significant improvements.
  • 35% achieved remission.

The big picture

  • DBS is already used for Parkinson’s disease.
  • Theta activity may predict treatment response.

What they're saying

  • Skepticism about availability and effectiveness.
  • Curiosity about comparison to ECT.

Caveats

  • Open label trial may introduce bias.
  • Further research needed.

What’s next

  • Results of a double-blinded trial coming soon.