Existing transplant drug slows type 1 diabetes progression
A transplant drug shows promise in slowing type 1 diabetes in youth.
Why it matters
- First potential therapy to modify type 1 diabetes after diagnosis.
- Uses an existing, affordable drug.
By the numbers
- 117 participants aged 5-25.
- 2.5 mg/kg dose most effective, but with more side effects.
- 0.5 mg/kg dose also effective, with fewer side effects.
The big picture
- Could change how type 1 diabetes is managed.
- Repurposed drug could be more accessible.
What they're saying
- Findings are promising for slowing loss of insulin-producing cells.
Caveats
- Higher doses had significant side effects.
- Study size was relatively small.
What’s next
- Further research to confirm and optimize treatment.