Gene therapy cures 95% of children with rare immune condition.

Gene therapy shows 100% survival and 95% cure rate in children with ADA-SCID over 7.5 years.

Why it matters

  • First large-scale study showing long-term safety and efficacy of gene therapy for ADA-SCID.
  • Offers a potential cure for a previously life-threatening condition.
  • Demonstrates promise for gene therapy in treating other genetic diseases.

By the numbers

  • 62 patients treated.
  • 7.5 years average follow-up.
  • 100% survival rate.
  • 95% cure rate.

The big picture

  • ADA-SCID is a rare, life-threatening immune deficiency.
  • Gene therapy could replace current treatments like enzyme replacement and bone marrow transplants.
  • Efforts are underway to make this therapy more widely available.

What they're saying

  • Experts highlight the potential of gene therapy for other diseases, including cancers.
  • Ethical considerations and accessibility remain important topics.

Caveats

  • Study focuses on a specific rare condition.
  • Long-term effects are still being studied.

What’s next

  • Plans to seek market authorization in the UK.
  • Continued research into gene therapy for other conditions.