Gum disease hits men harder due to inflammation

Men suffer more from gum disease due to inflammation, study finds.

Why it matters

  • Men are more affected by gum disease than women, and now we know why.
  • This could lead to sex-specific treatments.

By the numbers

  • 6,200 human samples analyzed.
  • 40% of US adults aged 30+ have periodontitis (50% of men, 33% of women).

The big picture

  • Findings could help treat gum disease in both sexes through different interventions.

What they're saying

  • Julie Marchesan: Study pinpoints inflammasome as a driver of male-biased periodontitis, paving way for sex-specific treatments.

Caveats

  • Study needs further research for treatments.

What’s next

  • Developing treatments targeting IL-1β.
  • Understanding mechanisms in females.