Healthy gut may boost mental health

Gut microbes may influence brain chemistry, offering new mental health treatment avenues.

Why it matters

  • Mental health disorders affect nearly 970 million people worldwide.
  • Current treatments are ineffective for many, highlighting a need for new approaches.

By the numbers

  • Nearly one in seven people globally live with a mental health disorder.
  • Up to one-third of patients do not respond to current medications.

The big picture

  • Gut microbes can change brain chemistry and stress responses in animal models.
  • Early trials show probiotics, diet changes, and FMT can improve mood and anxiety.
  • Psychiatric medications can alter the microbiome, further supporting the gut-brain link.

What they're saying

  • Anecdotal evidence supports gut-brain connection; users report improved mental health with better gut health.
  • Some question the novelty of the finding, suggesting it's been known for a while.

Caveats

  • More research needed, including long-term studies and larger, diverse populations.
  • Most evidence from animal models; human studies are early-stage.

What’s next

  • Future studies to track gut changes over time and include diverse populations.
  • More clinical trials on probiotics, diet changes, and FMT needed.