New antibody blocks malaria in trial

New antibody fully protects against malaria in trial, offering hope for high-risk regions.

Why it matters

  • Could transform malaria prevention in high-risk regions.
  • Offers potential for immediate, long-lasting protection with a single dose.

By the numbers

  • 38 participants in the trial.
  • 100% protection in highest dose group vs. 0% in placebo.

The big picture

  • Could provide months of protection with a single dose, unlike vaccines.
  • Testing in children in Uganda has begun.

What they're saying

  • Lead researcher calls it a "fundamentally different way to stop infection."
  • Co-author highlights it as a step forward for health equity.

Caveats

  • Early-stage trial with small sample size.

What’s next

  • Optimizing dosing and reducing costs for use in endemic regions.
  • Trials in young children in Uganda underway.