New 'caged' drug targets cancer safely in mice
New 'caged' drug targets cancer safely by activating only in tumors in mice.
Why it matters
- Offers safer way to use immune system to fight cancer
- Current treatments can cause harmful inflammation elsewhere
- New method targets only tumors, sparing healthy tissue
By the numbers
- Tested in mice and zebrafish
- Drug activated almost exclusively in tumors
The big picture
- Could lead to safer, more precise cancer treatments
- Potential for targeted drug delivery in other applications
What they're saying
- Lead researcher compares method to safe packages unlocking only at tumors
- First author sees potential for safer, more precise medicines
Caveats
- Study in mice and zebrafish; human trials needed to confirm safety and efficacy
What’s next
- Further studies and human trials planned