New CRISPR Technique Targets Genetic Diseases
New CRISPR technique removes DNA tags to switch genes on, offering safer treatment for genetic diseases.
Why it matters
- Confirms methylation directly silences genes.
- Offers safer treatment for genetic diseases by avoiding DNA cuts.
By the numbers
- Tested on human cells in a lab.
- Plans for animal testing and clinical trials next.
The big picture
- Could transform treatment for genetic diseases like Sickle Cell.
- Gentler approach with potentially fewer side effects.
What they're saying
- Technique to demethylate specific genes is a significant achievement.
- Methylation can work like a volume dial, not just an on/off switch.
Caveats
- Work done in lab on human cells, not yet in living organisms.
- Future testing in animals and clinical trials needed.
What’s next
- Animal testing and clinical trials planned.
- Exploring other CRISPR-related tools and modifications.