New diabetes pill matches Ozempic for weight loss

A new pill for type 2 diabetes, orforglipron, shows weight loss results comparable to injectable Ozempic.

Why it matters

  • New oral treatment option for weight loss in type 2 diabetes.
  • Could shift treatment paradigms due to convenience.

By the numbers

  • 1,613 participants with type 2 diabetes.
  • Average weight loss of 9.6% on highest dose.
  • Study duration: 72 weeks across 10 countries.

The big picture

  • Orforglipron offers an effective oral alternative to injectable GLP-1 drugs.
  • Improvements seen in blood sugar, heart, and inflammation markers.

What they're saying

  • Excitement about potential widespread use and lower cost compared to injectables.
  • Concerns about reliance on medication over lifestyle changes.

Caveats

  • Study funded by pharmaceutical company Eli Lilly.
  • Drug not yet FDA approved; expected availability in 2026.

What’s next

  • Further studies and FDA approval process.