New vulnerability found in Lyme disease bacteria

Manganese: both shield and weakness in Lyme disease bacteria.

Why it matters

  • Lyme disease affects about 476,000 people annually in the U.S.
  • Current treatments have limitations and no approved vaccines exist.

By the numbers

  • 476,000 annual Lyme disease diagnoses in the U.S.

The big picture

  • Manganese acts as both defense and weakness in Borrelia burgdorferi.
  • New therapies could target manganese balance to combat Lyme disease.

What they're saying

  • Comments highlight the dual role of manganese as a defense and vulnerability.

Caveats

  • Further research needed to develop new therapies based on this discovery.

What’s next

  • Potential development of drugs that disrupt manganese balance in the bacteria.