Pfizer mRNA flu shot outperforms traditional vaccine in trial

Pfizer's mRNA flu vaccine shows 34.5% fewer illnesses than traditional shots in Phase 3 trial.

Why it matters

  • mRNA technology improves flu protection.
  • Faster production could lead to better strain matching each year.

By the numbers

  • Trial included over 18,000 adults.
  • mRNA vaccine showed 34.5% fewer flu-like illnesses.
  • 57 cases in mRNA group vs. 87 in traditional group.

The big picture

  • mRNA vaccine could be a game-changer.
  • Approval might be challenging due to skepticism and funding cuts.

What they're saying

  • Dr. Buddy Creech called it a "game-changer."
  • Dr. Peter Hotez expressed concern about lack of interest in mRNA science.

Caveats

  • More side effects with mRNA vaccine (e.g., 5.6% fever vs. 1.7%).
  • Approval may face hurdles due to funding cuts and skepticism.

What’s next

  • Pfizer in discussions with regulators; no timeline for approval.