Popular hair loss drug linked to higher suicide risk

Finasteride users face higher suicide risk, new study finds.

Why it matters

  • Finasteride, used for hair loss, is linked to higher risks of depression, anxiety, and suicidal thoughts.
  • The study combines findings from multiple research studies, highlighting a significant mental health concern.
  • Raises questions about the regulation and safety of cosmetic drugs.

By the numbers

  • Over 30 years, 19,320 suicides were expected among users.
  • By 2024, 320 suicides were reported.
  • Expected suicidal thoughts: 414,000; reported by 2024: 1,062.

The big picture

  • Finasteride affects brain chemicals, potentially causing lasting changes and mental health issues.
  • Underreporting of side effects is a major concern due to various factors.
  • Calls for better post-marketing studies and stricter regulation of cosmetic drugs.

What they're saying

  • Users share personal anecdotes and concerns about the drug's effects.
  • Questions raised about the study's control for pre-existing conditions like depression due to hair loss.
  • General awareness of depressive side effects among users.

Caveats

  • The study is a review, which may have inherent limitations.
  • Underreporting of side effects could skew the data.
  • Systemic failures in pharmacovigilance are noted.

What’s next

  • More rigorous post-marketing studies are needed.
  • Better regulation and monitoring of cosmetic drugs like finasteride.