Psilocin may reduce alcohol consumption by calming stress-related brain activity

Psilocin, derived from magic mushrooms, reduces alcohol consumption by calming stress-related brain activity in mice.

Why it matters

  • Psilocin, derived from psilocybin, may help treat alcohol addiction by reducing stress-related brain activity.
  • This study provides insights into the biological mechanisms behind psychedelics' effects.

By the numbers

  • The study was conducted on female mice, which tend to consume more alcohol than males.
  • Psilocin's effects were temporary, with alcohol consumption returning to previous levels once the drug's effects subsided.

The big picture

  • The findings align with clinical observations that psychedelics can improve emotional regulation and stress resilience.
  • This research could help refine therapeutic approaches for alcohol use disorder and other mental health conditions.

What they're saying

  • I'm just happy these things are being researched. People who have used shrooms mostly already know this, and it's good that it's getting some scientific backing.
  • Tell me things I knew at 16.

Caveats

  • The study is preclinical and conducted on mice; further research is needed to confirm these findings in humans.

What’s next

  • Further research is needed to understand how psilocin affects brain function related to addiction in humans.
  • Scientists aim to refine therapeutic approaches and improve outcomes for people with alcohol use disorder.