Psilocybin eases pain, depression in mice

Psilocybin in mice: rewires brain circuits, eases pain and depression for up to two weeks.

Why it matters

  • Psilocybin may rewire brain circuits, offering a non-addictive alternative to opioids.
  • Could lead to new treatments for chronic pain and depression.

By the numbers

  • Single dose of psilocybin.
  • Up to two weeks of relief in mice.

The big picture

  • Chronic pain and depression are major health challenges.
  • Opioids are addictive; psilocybin could be a safer option.
  • Early-stage research but promising for future therapies.

What they're saying

  • Some question how depression is measured in mice.
  • Anecdotal reports vary: some see relief, others report worsened symptoms.

Caveats

  • Study limited to mice; human trials needed.
  • Individual experiences with psilocybin vary widely.

What’s next

  • Human studies to confirm efficacy and safety.
  • Further research into long-term effects and mechanisms.