Scientists identify genetic switch key to human brain uniqueness
A genetic switch, HAR123, may explain human brain uniqueness and cognitive flexibility.
Why it matters
- Understanding what makes the human brain unique could help in comprehending neurodevelopmental disorders like autism.
By the numbers
- HAR123 is a 442-nucleotide sequence that has evolved rapidly in humans.
The big picture
- This discovery could lead to better understanding of human brain evolution and molecular mechanisms behind neurodevelopmental disorders.
What they're saying
- Some doubt if a single genetic switch can explain all brain flexibility, but it's still an interesting finding.
Caveats
- More research is needed to fully understand HAR123's molecular action and its role in human-specific neural traits.
What’s next
- Further studies could explore HAR123's links to other areas, like psychedelics, and its presence in Neanderthals.