Sound waves and holograms control brain circuits

New technique uses sound waves and holograms to control brain circuits in mice, paving the way for non-invasive treatments.

Why it matters

  • First visual evidence of brain circuit activation using ultrasound waves and holograms.
  • Potential for non-invasive treatments of neurological diseases and mental health disorders.

By the numbers

  • 512 ultrasound emitters used to create holograms.
  • Neurons became 10 times more sensitive to ultrasound when targeting distributed circuits.

The big picture

  • Technique could lead to safer, non-invasive brain treatments.
  • Current applications are being tested for Parkinson's disease.

What they're saying

  • Researchers hope to translate this work into human treatments.
  • Ethical questions raised about brain manipulation techniques.

Caveats

  • Study conducted in mice; human trials needed.
  • Need to calibrate ultrasound waves to avoid brain tissue damage.

What’s next

  • Explore activating more complex neural circuits.
  • Test ultrasound on deeper brain circuits.