Stanford researchers link Epstein-Barr virus to lupus

Stanford researchers discover how Epstein-Barr virus triggers lupus, offering hope for new treatments.

Why it matters

  • Lupus affects over 200,000 Americans and has no cure.
  • Discovery links EBV to lupus, paving way for targeted treatments.

By the numbers

  • 200,000: Americans affected by lupus.
  • 1 in 400: B cells infected with EBV in lupus patients vs. 1 in 10,000 in healthy individuals.

The big picture

  • New treatments could target EBV-infected B cells.
  • Therapies may induce remission in lupus patients.

What they're saying

  • Lead researcher Dr. William Robinson: Study solves longstanding mystery.
  • UCSF's Dr. Monica Gandhi: Findings suggest potential therapeutics.
  • Public comments express hope for new treatments.

Caveats

  • Observational study; causal mechanisms need confirmation.
  • Timeline for new treatments unclear.

What’s next

  • Development of therapies targeting EBV-infected B cells.
  • Exploration of CAR-T cell therapy for remission.