Study reveals brain secrets of superagers who stay sharp into their 80s.
Superagers' brains resist Alzheimer's proteins and have unique neuron structures, new study finds.
Why it matters
- Superagers retain sharp memories into their 80s, defying typical cognitive decline.
- Their brains resist Alzheimer's-related protein buildup and have unique neuron structures.
By the numbers
- Study monitored 290 people aged 80+ since 2000.
- Examined 79 donated brains of superagers.
- Superagers can recall at least 9 words out of 15, typical of people decades younger.
The big picture
- Superagers have larger entorhinal neurons and more von Economo neurons, contributing to cognitive resilience.
- High extroversion is a common trait among superagers.
- Biological factors seem crucial as some superagers lead less healthy lifestyles.
What they're saying
- Personal anecdotes highlight real-life examples of cognitive resilience in old age.
- Suggestions that multilingualism might help maintain brain health.
Caveats
- Findings need validation in other populations.
- Study suggests a significant biological component, but lifestyle factors may also play a role.
What’s next
- Research may lead to pharmaceuticals promoting superager brain settings and Alzheimer's resistance.
- Further investigation into genes affecting cognition as we age.