Vitamin D2 supplements may reduce D3 levels

Vitamin D2 supplements may reduce D3 levels, affecting immune function.

Why it matters

  • Vitamin D is essential for immune function and overall health.

By the numbers

  • Meta-analysis of 11 studies with 655 participants.

The big picture

  • D2 supplements reduce D3 levels but still provide sufficient vitamin D.
  • D3 may be more beneficial for immune support.
  • Plant-based D3 supplements are emerging.

What they're saying

  • One comment notes the headline is misleading; D3's effect on D2 levels is unclear.
  • Another suggests D3 is more effective and commonly found in supplements.

Caveats

  • Mechanism behind D2 reducing D3 levels is unclear.
  • Study doesn't recommend stopping D2 supplements.

What’s next

  • More research needed on mechanisms and long-term effects.
  • Development of plant-based D3 supplements ongoing.